I-TianJia Yokungeza Ukudla Umkhiqizi I-Choline chloride
I-Choline chloride iyinhlanganisela ye-organic ene-chemical formula C5H14ClNO.I-crystal hygroscopic emhlophe, ayinaphunga, futhi inephunga elimnandi.Iphoyinti lokuncibilika 305 ℃.Isixazululo esinamanzi esingu-10% esine-pH 5-6 asizinzile kusisombululo se-alkaline.Lo mkhiqizo uncibilika kalula emanzini ne-ethanol, kodwa hhayi ku-ether, petroleum ether, benzene, ne-carbon disulfide.Ubuthi obuphansi, i-LD50 (igundane, ngomlomo) 3400 mg/kg.Isetshenziselwa ukwelapha isibindi esinamafutha kanye ne-cirrhosis.Futhi isetshenziswa njengesengezo sokuphakelayo sezinkukhu nemfuyo, ingashukumisa ama-ovari ukuthi akhiqize amaqanda amaningi, udoti, futhi athole isisindo ezinkukhu, izinhlanzi, nezinye izilwane.
Ukusetshenziswa:imithi, amakhemikhali, imikhiqizo yokudla, imikhiqizo yezolimo, izithasiselo zokudla
Njengesengezo sokuphakelayo, i-choline chloride inemiphumela elandelayo yomzimba:kungavimbela ukunqwabelana kwamafutha kanye nokonakala kwezicubu esibindini nasezinso;Iyakwazi ukukhuthaza ukuhlanganiswa kabusha kwama-amino acid;Ingathuthukisa izinga lokusetshenziswa kwama-amino acid, ikakhulukazi i-amino acid methionine ebalulekile, emzimbeni.E-Japan, i-98% ye-choline chloride isetshenziswa njengesengezo sokuphakelayo ezilwaneni ezinjengezinkukhu, izingulube, izinkomo zenkomo, nezinhlanzi nezimfanzi.Iningi lazo licutshungulwa libe yimpushana, futhi indlela yokulungiselela i-50% yempushana iwukuba ungeze ngaphambili i-excipient yosayizi wezinhlayiyana ezifanele ku-mixer, bese uphonsa engeza isixazululo samanzi se-choline chloride, esixutshwe futhi somiswe.Ezinye izimpushana zomkhiqizo nazo zihlanganiswe namavithamini, amaminerali, izidakamizwa, njll. I-Choline chloride iyisidakamizwa sikavithamini B esisetshenziselwa izifo ezifana ne-hepatitis, ukuwohloka kwesibindi, isifo sokusha kwesibindi, kanye ne-anemia eyingozi.
I-Choline iyisakhi esibalulekile se-lecithin, edlala indima ebalulekile ekugcineni ukwakheka okujwayelekile nokusebenza kwamangqamuzana olwelwesi lwamaseli, kanye ne-lipid metabolism, futhi ingavimbela ukubekwa kwamafutha esibindi.
I-Choline iphinde ibe yingxenye ebalulekile ekuhlanganisweni kwe-neurotransmitter acetylcholine, futhi isebenza njengomnikeli we-methyl ekuhlanganiseni kwe-methionine.
I-Choline chloride isetshenziselwa ukukhuthaza ukukhula kanye nokuntuleka kwe-choline.
Okuphakelayo kuqukethe inani elithile le-choline, elingabuye lihlanganiswe isibindi emzimbeni, ngakho ngokuvamile akubangeli ukuntuleka kwe-choline.Kodwa-ke, izinkukhu zamabhulukwe amazambane, ikakhulukazi amaphuphu, zinesidingo esikhulu se-choline futhi zine-synthesis ephansi.Uma okuphakelayo kungengeziwe ngokwanele noma kuphakelwa ukudla okuphansi kwe-choline (njengombila) isikhathi eside, kulula ukubangela ukuntula.
Lapho izinkukhu ezifuywayo zihlushwa izifo zesibindi futhi zinamazinga anganele kavithamini B2 kanye ne-folic acid ekudleni kwazo, kungabangela nokuntuleka kwe-choline.Lapho ukuntuleka kwe-choline kwenzeka, izingulube zibonisa ukukhula kancane, ukuqina kwamalunga kanye ne-dyskinesia, ukufakwa kwamafutha esibindi, nokuncipha kokuzala.Izinkukhu zibonisa ukukhula kancane, i-tibia emfushane neyigqinsi, ejwayele ukuhlukaniswa kwe-tendon, isifo sesibindi esinamafutha, nokuncipha kokukhiqizwa kwamaqanda.
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