I-Choline chloride
I-Choline chloride iyinhlanganisela yezinto eziphilayo enefomula yamakhemikhali i-C5H14ClNO. Iyikristalu emhlophe e-hygroscopic, ayinaphunga, futhi inephunga lenhlanzi. Indawo yokuncibilika ingu-305 ℃. Isixazululo samanzi esingu-10% esine-pH 5-6 asizinzile esixazululweni se-alkaline. Lo mkhiqizo uncibilika kalula emanzini nase-ethanol, kodwa hhayi ku-ether, i-petroleum ether, i-benzene, kanye ne-carbon disulfide. Ubuthi obuphansi, i-LD50 (igundane, ngomlomo) 3400 mg/kg. Isetshenziselwa ukwelapha isibindi esinamafutha kanye ne-cirrhosis. Iphinde isetshenziswe njengesithako sokudla sezinkukhu nezilwane, ingakhuthaza ama-ovari ukuthi akhiqize amaqanda amaningi, udoti, futhi andise isisindo sezinkukhu, izinhlanzi, nezinye izilwane.
Ukusetshenziswa:imithi, amakhemikhali, imikhiqizo yokudla, imikhiqizo yezolimo, izithasiselo zokudla
Njengesengezo sokudla, i-choline chloride inemiphumela elandelayo yomzimba:kungavimbela ukuqongelela kwamafutha kanye nokuwohloka kwezicubu esibindini nasezinso; Kungakhuthaza ukuhlanganiswa kabusha kwama-amino acid; Kungathuthukisa izinga lokusetshenziswa kwama-amino acid, ikakhulukazi i-amino acid methionine ebalulekile, emzimbeni. EJapane, ama-98% e-choline chloride asetshenziswa njengesithako sokudla kwezilwane ezifana nezinkukhu, izingulube, izinkomo zenyama yenkomo, kanye nezinhlanzi nama-shrimp. Iningi lazo liyacutshungulwa libe yimpuphu, futhi indlela yokulungiselela i-50% impuphu ukufaka kusengaphambili i-excipient efanele yosayizi wezinhlayiya ku-mixer, bese uphonsa ufaka isixazululo samanzi se-choline chloride, esixutshwe futhi somiswe. Amanye ama-powder omkhiqizo nawo ahlanganiswa namavithamini, amaminerali, izidakamizwa, njll. I-Choline chloride iyisidakamizwa se-vitamin B esisetshenziselwa izifo ezifana ne-hepatitis, ukuwohloka kwesibindi, i-cirrhosis yasekuqaleni, kanye ne-anemia eyingozi.
I-Choline iyisakhi esibalulekile se-lecithin, edlala indima ebalulekile ekugcineni isakhiwo kanye nomsebenzi ojwayelekile wama-membrane esisele, kanye ne-lipid metabolism, futhi ingavimbela ukugcinwa kwamafutha esibindini.
I-Choline nayo iyisici esibalulekile ekwakhiweni kwe-neurotransmitter acetylcholine, futhi isebenza njengomnikeli we-methyl ekwakhiweni kwe-methionine.
I-Choline chloride isetshenziselwa ukukhuthaza ukukhula kanye nokuntuleka kwe-choline.
Ukudla kuqukethe inani elithile le-choline, elingakhiwa futhi yisibindi emzimbeni, ngakho ngokuvamile akubangeli ukuntuleka kwe-choline. Kodwa-ke, izinkukhu zama-potato pants, ikakhulukazi amaphuphu, zinesidingo esikhulu se-choline futhi zinokukhiqizwa okuphansi. Uma ukudla kungafakwanga ngokwanele noma kungaphiwa ukudla okune-choline ephansi (njengommbila) isikhathi eside, kulula ukubangela ukuntuleka.
Uma izinkukhu zasekhaya zihlushwa izifo zesibindi futhi zinganele amazinga e-vitamin B2 kanye ne-folic acid ekudleni kwazo, kungabangela nokuntuleka kwe-choline. Uma kwenzeka ukuntuleka kwe-choline, izingulube zibonisa ukukhula okuhamba kancane, ukuqina kwamalunga kanye ne-dyskinesia, ukugcinwa kwamafutha esibindi, kanye nokusebenza kokuzala okunciphile. Izinkukhu zibonisa ukukhula okuhamba kancane, i-tibia emfushane nejiyile, evame ukuhlukana kwemisipha, isifo sesibindi esinamafutha, kanye nokwehla kokukhiqizwa kwamaqanda.
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